MABC72 | Anti-TNF receptor-associated factor 1 (TRAF1) Antibody, clone 11B2.2

100 µg  
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      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Catalogue NumberMABC72
      DescriptionAnti-TNF receptor-associated factor 1 (TRAF1) Antibody, clone 11B2.2
      Alternate Names
      • TNF receptor-associated factor 1
      • Epstein-Barr virus-induced protein 6
      Background InformationTNF receptor-associated factor 1 is an adapter protein belonging to the TRAF family. It contains the conserved C-terminal TRAF domain that is required for trimerization and interaction with cell surface receptors such as CD30, CD40, OX40, AITR, and RANK. TNF receptor-associated factor 1 also interacts with a variety of cytoplasmic proteins such as RIP1, RIP2, A20 and TRIP. Among other functions, TNF receptor-associated factor 1 is involved in regulating NF-kB and JNK signaling. TNF receptor-associated factor 1 is expressed in the lung, testis, and spleen, and can be induced by TNF-α, interleukin (IL)-1 or EBV infection. Previous studies have suggested that TNF receptor-associated factor 1 may play a role in oncogenesis.
      Product Information
      • Raji cell lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationAnti-TNF receptor-associated factor 1 (TRAF1) Antibody, clone 11B2.2 detects level of TNF receptor-associated factor 1 (TRAF1) & has been published & validated for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human TNF receptor-associated factor 1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TRAF1
      • EBI6
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~46 kDa observed
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Raji cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected TNF receptor-associated factor 1 on 10 µg of Raji cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information

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      Life Science Research > Antibodies and Assays > Primary Antibodies