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AG723-KC | C-Reactive Protein-KC

AG723-KC
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      Overview

      Replacement Information
      Description
      Catalogue NumberAG723-KC
      DescriptionC-Reactive Protein-KC
      References
      Product Information
      FormatPurified
      PresentationLiquid in 100mM NaCl, 10mM Tris-HCl with 0.1% sodium azide, 2mM Calcium
      Applications
      Key Applications
      • Positive Control
      Biological Information
      Purity>98% by SDS-PAGE.
      SourceHuman pleural fluid, negative for HBsAg, anti-HCV, anti-HIV-1 and anti-HIV-2.
      Gene Symbol
      • CRP
      • MGC149895
      • PTX1
      • MGC88244
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P02741 # Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
      COFACTOR: Binds 2 calcium ions per subunit.
      SIZE: 224 amino acids; 25039 Da
      SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Found in plasma.
      SIMILARITY: SwissProt: P02741 ## Belongs to the pentaxin family. & Contains 1 pentaxin domain.
      MISCELLANEOUS: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceNo precipitin bands when tested at 2 mg/mL against anti-whole human serum.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material SizeBulk packaging. Please inquire.
      Transport Information
      Supplemental Information
      Specifications

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      Alternative Packsize

      Catalogue Number Description  
      AG723 C-Reactive Protein Show Pricing & Availability

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      Categories

      IVD/OEM Materials & Reagents > Bulk & Custom Antibodies > Primary Bulk Antibodies by Target > Tumor Markers & Antigens