171617 Anti-β-Amyloid Precursor-Like Protein 2, Full-length Rabbit pAb

171617
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.





      Recognizes the APLP2 protein. Does recognize APP or APLP1.
    • Antibody Target Gene Symbol: APLP2
    • Target Synonym: AI790698, ALID2, APPH, APPL2, CDEBP, LOC64312, WALPLP2, YWK-II
    • Entrez Gene Name: amyloid beta (A4) precursor-like protein 2
    • Hu Entrez ID: 334 (Related Antibodies: 171616)
    • Mu Entrez ID: 11804
    • Rat Entrez ID: 64312
    • Catalogue Number171617
      Brand Family Calbiochem®
      SynonymsAnti-APLP2, Anti-D2-II
      References
      ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
      Crain, B.J., et al. 1996. Am. J. Pathol. 149, 1087.
      Thinakaran, G., et al. 1995. J. Neurosci. 15, 6314.
      Thinakaran, G., and Sisodia, S.S. 1994. J. Biol. Chem. 269, 22099.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Applications
      Key Applications Immunoprecipitation
      Paraffin Sections
      Frozen Sections
      Immunoblotting (Western Blotting)
      Immunofluorescence
      Application NotesFrozen Sections (1:1000)
      Immunoblotting (1:5000-1:20,000)
      Immunofluorescence (1:250-1:500; not tested on cultured cells)
      Immunoprecipitation (1-2 µl per mg cell or tissue lysate)
      Paraffin Sections (1:1000)
      Application CommentsDoes not cross-react with APP and APLP1. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenfull-length mouse APLP2
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      171617

      References

      Reference overview
      Walsh D.M., et al. 2002. Biochemistry in press.
      Crain, B.J., et al. 1996. Am. J. Pathol. 149, 1087.
      Thinakaran, G., et al. 1995. J. Neurosci. 15, 6314.
      Thinakaran, G., and Sisodia, S.S. 1994. J. Biol. Chem. 269, 22099.

      Brochure

      Title
      Alzheimer's Disease Brochure & Technical Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-September-2009 JLN
      SynonymsAnti-APLP2, Anti-D2-II
      ApplicationFrozen Sections (1:1000)
      Immunoblotting (1:5000-1:20,000)
      Immunofluorescence (1:250-1:500; not tested on cultured cells)
      Immunoprecipitation (1-2 µl per mg cell or tissue lysate)
      Paraffin Sections (1:1000)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the APLP2 protein.
      BackgroundAmyloid precursor-like protein 2 (APLP2) is a member of a family of related polypeptides that includes amyloid precursor proteins (APP) and amyloid precursor-like protein 1 (APLP1). APP generates beta-amyloid peptide, deposits of which form the amyloid plaques that characterize Alzheimer’s disease.
      HostRabbit
      Immunogen speciesMouse
      Immunogenfull-length mouse APLP2
      IsotypeIgG
      Specieshuman, mouse, rat
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsDoes not cross-react with APP and APLP1. Variables associated with assay conditions will dictate the proper working dilution.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
      Crain, B.J., et al. 1996. Am. J. Pathol. 149, 1087.
      Thinakaran, G., et al. 1995. J. Neurosci. 15, 6314.
      Thinakaran, G., and Sisodia, S.S. 1994. J. Biol. Chem. 269, 22099.