Chromolith® Guard Cartridges and Kit

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Extend Your Column’s Lifetime

Chromolith® guard cartridgesChromolith® monolithic HPLC columns are already well known for their robustness and longevity. For even better protection of your analytical columns, Merck also offers Chromolith® guard cartridges and kits. Chemically modified with hydrophobic n-octadecyl (C18) groups on the surface of a monolithic silica rod, the guard columns are ideal for reversed-phase chromatography.

Guard Cartridges

Available in 5 and 10 mm lengths, Chromolith® HPLC guard cartridges are extremely easy to use. Due to the general benefits of monolithic technology, and the convenience of Chromolith® guard columns, they are also popular for the protection of classical packed columns. Guard columns should be frequently changed to avoid excessive accumulation of impurities.

Guard Cartridge Starter Kit

The Chromolith® guard cartridge kit includes everything you need to significantly enhance the lifetime of your columns: a guard cartridge holder, and three guard cartridges.

Features and Benefits

  • Protection against chemical or mechanical contamination
  • Significantly longer column lifetime 
  • Suitable for reversed-phase chromatography
  • Available as a starter kit

Specifications

Column Chromolith® Performance RP-18 endcapped, 100-2 mm with precolumn Chromolith® RP-18 endcapped 5-2 mm Chromolith® Performance RP-18 endcapped 100-2 mm without pre-column 
Mobile phase Acetonitrile/ water 60/40 Acetonitrile/ water 60/40
Flow rate 0.38 mL/min 0.38 mL/min
Pressure 20 bar 20 bar
Detection UV 254 nm UV 254 nm
Anthracene

N/m
TUSP
K´-value

113540
1.14
3.79

N/m
TUSP
K´-value

115460
1.07
3.90

Sample

1. Thiourea
2. Biphenyl-2-ol
3. Progesterone
4. Hexanophenone
5. Anthracene

1. Thiourea
2. Biphenyl-2-ol
3. Progesterone
4. Hexanophenone
5. Anthracene

Diagram

Chromolith® Performance RP-18 endcapped 100-2 mm with pre-column

Chromolith® Performance RP-18 endcapped 100-2 mm with pre-column

 
 
 
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