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111609 Histosec® pastilles

Purchase on Sigma-Aldrich


Replacement Information


Catalogue NumberPackaging Qty/Pack
1116091000 Plastic bottle 1 kg
1116092504 Plastic bag 4 x 2.5 kg
1116099025 Fibre carton 25 kg
Catalogue Number111609
SynonymsEmbedding agents for microscopy, Embedding agent, Histosec®
OverviewHistosec® pastilles is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available without the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.
The Histosec® pastilles are well soluble with the Intermedia Xylene or xylene substitutes (such as Neo-Clear(R)).
The paraffin is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes.
Product Information
HS Code2712 20 90
ApplicationParaffin embedding medium. Contains DMSO. Solidification point 56-58°C
Biological Information
Physicochemical Information
Flash point>100 °C
Bulk density400 kg/m3
Materials Information
Toxicological Information
LD 50 dermalLD50 Rabbit > 3000 mg/kg
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKNWG not water endangering
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Supplemental Information
Solidification point (rotating thermometer method)56 - 58 °C
Effect of heating (at 60 °C/100 g)clear melt within max. 20 hours
Solubility in xylene (at 20 °C/0.1 g in 5 ml)clear solute within max. 20 hours
Cutting results (4 µm slices)conforms
Solubility of slices in xylene< 50 seconds


Histosec® pastilles SDS


Safety Data Sheet (SDS) 

Histosec® pastilles Certificates of Analysis

Product Number PackagingSpecificationLot Number
1116091000 Plastic bottlePDF Specification Document
1116092504 Plastic bagPDF Specification Document
1116099025 Fibre cartonPDF Specification Document


Alles für die Histologie. Schnell und zuverlässig.
Products for Microscopy-The Color of Life Science

Instructions for Use

111609 - Histosec® pastillas - ponto de solidificação 56-58 GRAD C agente de inclusão para histologia
111609 Histosec® pastilles solidification point 56-58°C embedding agent for histology

Related Products & Applications

Alternative Products

Catalogue Number Description
107164 Paraffin pastilles
115161 Histosec® pastilles (without DMSO)

Related Products

Catalogue Number Description
115161 Histosec® pastilles (without DMSO)

Accessories (Secondary)

Catalogue Number Description
100496 Formaldehyde solution 4%, buffered, pH 6.9

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IVD/OEM Materials & Reagents > Microscopy > Universal Reagents > Embedding
IVD/OEM Materials & Reagents > Microscopy > Histology > Auxiliaries for Histology