Why Test for Mycoplasmas in
Biopharmaceutical Manufacturing?

Request Information

Mycoplasma contamination is a widespread and reoccurring problem in a wide variety of cell culture systems. These micro-organisms, which belong to the class Mollicutes, are comparatively small (0.2 – 0.3 µm), lack a cell wall and are thus not susceptible to penicillins or other antibiotics that act on this structure, and they show tolerance to many other antibiotics. This allows them to grow to high titers in culture media without exhibiting typical bacterial contamination signs, like turbidity.

Contamination of a bioreactor can lead to significant loss of time, materials and revenue unless identified early in the process. In fact, microbial contamination is one of the primary reasons for batch failure in biopharmaceutical production. It is therefore important to test for mycoplasmas at various points in the manufacturing process. To this end, Merck provides both compendial and rapid solutions for reliable Mycoplasma detection.

Mycoplasma Testing
 
 
Mycoplasma Culture Media Brochure

Brochure
Mycoplasma Culture Media

Download Here
MilliPROBE® System Brochure

Brochure
MilliPROBE® System

Download Here
 

Events

Oct 16
16/10/17 - 18/10/17
12th Annual PDA Global Conference on Pharmaceutical Microbiology
Bethesda North Marriott Hotel
Bethesda, MD, USA
Industrial Biomonitoring North America 20171016
Nov 07
07/11/17 - 08/11/17
PharmaLab Congress
Swissôtel Düsseldorf / Neuss
Dusseldorf, Germany
Water Purification,Reagents Chemicals and Labware,Life Science Research,Industrial Biomonitoring,Analytics and Sample Preparation Europe 20171107
Nov 14
14/11/17 - 16/11/17
A3P Annual Congress
Congress Center - Espace Bellevue
Biarritz, France
Industrial Biomonitoring,Biopharmaceutical Manufacturing Europe 20171114