05-23-0317 Atriopeptin III, Rat

05-23-0317
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₀₇H₁₆₅N₃₅O₃₄S₂ 90817-13-3
      Description
      OverviewDelays outward K+ current in cardiac cells. A guanylate cyclase activator. Increases cGMP levels and the permeability of endothelial cell monolayers.
      Catalogue Number05-23-0317
      Brand Family Calbiochem®
      SynonymsSSCFGGRIDRIGAQSGLGCNSFR
      References
      ReferencesBkaily, G., et al. 1993. J. Mol. Cell. Cardiol. 25, 1305.
      Mene, P., et al. 1993. Exp. Neurol. 1, 245.
      Geller, D.M., et al. 1984. Biochem. Biophys. Res. Commun. 120, 333.
      Product Information
      CAS number90817-13-3
      FormWhite to off-white lyophilized solid
      Hill FormulaC₁₀₇H₁₆₅N₃₅O₃₄S₂
      Chemical formulaC₁₀₇H₁₆₅N₃₅O₃₄S₂
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Ser-Ser-Cys³-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys¹⁹-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 3 → 19)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 to months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificates of Analysis

      TitleLot Number
      05-23-0317

      References

      Reference overview
      Bkaily, G., et al. 1993. J. Mol. Cell. Cardiol. 25, 1305.
      Mene, P., et al. 1993. Exp. Neurol. 1, 245.
      Geller, D.M., et al. 1984. Biochem. Biophys. Res. Commun. 120, 333.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsSSCFGGRIDRIGAQSGLGCNSFR
      DescriptionDelays outward K+ current in cardiac cells. A guanylate cyclase agonist. Increases cGMP levels and the permeability of endothelial cell monolayers.
      FormWhite to off-white lyophilized solid
      CAS number90817-13-3
      Chemical formulaC₁₀₇H₁₆₅N₃₅O₃₄S₂
      Peptide SequenceH-Ser-Ser-Cys³-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys¹⁹-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 3 → 19)
      Purity≥97% by HPLC
      Solubility5% acetic acid (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 to months at -20°C.
      Toxicity Standard Handling
      ReferencesBkaily, G., et al. 1993. J. Mol. Cell. Cardiol. 25, 1305.
      Mene, P., et al. 1993. Exp. Neurol. 1, 245.
      Geller, D.M., et al. 1984. Biochem. Biophys. Res. Commun. 120, 333.