110150 N-Acetyl-D-glucosaminyl-(β1,4)-N-acetylmuramyl-L-alanyl-D-isoglutamine

110150
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      OverviewImmunomodulator peptide with immunoadjuvant and protective activity against bacterial and viral infections. Exhibits tumorigenic and somnogenic effects. Unlike muramyl peptides, contains GlcNAc attached to muramic acid of muramyl peptide via β1,4 glycosidic bond. Poorly permeable through intestinal wall. However, its bioavailability can be increased by using it in water-in-oil microemulsion.
      Catalogue Number110150
      Brand Family Calbiochem®
      SynonymsGMDP
      References
      ReferencesLyons, K.C., et al. 2000. Int. J. Pharm. 199, 17.
      Campbell, M., et al. 1990. J. Immunol. 145, 1029.
      Product Information
      CAS number70280-03-4
      FormLyophilized
      Hill FormulaC₂₇H₄₄N₅O₁₆
      Chemical formulaC₂₇H₄₄N₅O₁₆
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      N-Acetyl-D-glucosaminyl-(β1,4)-N-acetylmuramyl-L-alanyl-D-isoglutamine MSDS

      Title

      Safety Data Sheet (SDS) 

      N-Acetyl-D-glucosaminyl-(β1,4)-N-acetylmuramyl-L-alanyl-D-isoglutamine Certificates of Analysis

      TitleLot Number
      110150

      References

      Reference overview
      Lyons, K.C., et al. 2000. Int. J. Pharm. 199, 17.
      Campbell, M., et al. 1990. J. Immunol. 145, 1029.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-April-2008 RFH
      SynonymsGMDP
      DescriptionImmunomodulator peptide with immunoadjuvant and protective activity against bacterial and viral infections. Exhibits tumorigenic and somnogenic effects. Unlike muramyl peptides, contains GlcNAc attached to muramic acid of muramyl peptide via β1,4 glycosidic bond. Poorly permeable through intestinal wall. However, its bioavailability can be increased by using it in water-in-oil microemulsion.
      FormLyophilized
      CAS number70280-03-4
      Chemical formulaC₂₇H₄₄N₅O₁₆
      Purity≥97% by HPLC
      SolubilityH₂O (1 mg/ml) or PBS (1 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesLyons, K.C., et al. 2000. Int. J. Pharm. 199, 17.
      Campbell, M., et al. 1990. J. Immunol. 145, 1029.