05-23-0151 Oxytocin

05-23-0151
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.





      Synthetic oxytocin. Principal uterus-contracting and lactation-stimulating hormone of posterior pituitary gland that causes a marked, but transient, relaxation of vascular smooth muscles. Induces differentiation of P19 embryonic stem cells to cardiomyocytes. Stimulates myometrial GTPase and phospholipase C via coupling to Gq/11α. Oxytocin is known to increase Na+ excretion.
      Catalogue Number05-23-0151
      Brand Family Calbiochem®
      References
      ReferencesPaquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.
      Product Information
      CAS number50-56-6
      FormLyophilized
      FormulationSupplied as an acetate salt. Sold on the basis of peptide content.
      Hill FormulaC₄₃H₆₆O₁₂N₁₂S₂
      Chemical formulaC₄₃H₆₆O₁₂N₁₂S₂
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Cys¹-Tyr-Ile-Gln-Asn-Cys⁶-Pro-Leu-Gly-NH₂ (disulfide bond: 1 → 6)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSRS7534000
      Safety Information
      R PhraseR: 20-62

      Harmful by inhalation.
      Possible risk of impaired fertility.
      S PhraseS: 22-36

      Do not breathe dust.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MSDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      05-23-0151

      References

      Reference overview
      Paquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.

      Citations

      Title
    • Cecily V. Bishop and Fredrick Stormshak. (2006) Nongenomic Action of Progesterone Inhibits Oxytocin-Induced Phosphoinositide Hydrolysis and Prostaglandin F2{alpha} Secretion in the. Endocrinology 147, 937-942.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      DescriptionSynthetic oxytocin. Principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland that causes a marked but transient relaxation of vascular smooth muscles. Stimulates myometrial GTPase and phospholipase C via coupling to Gq/11α. Oxytocin is known to increase Na+ excretion.
      FormLyophilized
      FormulationSupplied as an acetate salt. Sold on the basis of peptide content.
      CAS number50-56-6
      RTECSRS7534000
      Chemical formulaC₄₃H₆₆O₁₂N₁₂S₂
      Peptide SequenceH-Cys¹-Tyr-Ile-Gln-Asn-Cys⁶-Pro-Leu-Gly-NH₂ (disulfide bond: 1 → 6)
      Purity≥95% by HPLC
      Solubility5% Acetic acid (1 mg/ml)
      Storage -20°C
      Protect from moisture
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Harmful & Carcinogenic / Teratogenic
      Merck USA index14 6979
      ReferencesPaquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.
      Citation
    • Cecily V. Bishop and Fredrick Stormshak. (2006) Nongenomic Action of Progesterone Inhibits Oxytocin-Induced Phosphoinositide Hydrolysis and Prostaglandin F2{alpha} Secretion in the. Endocrinology 147, 937-942.