05-23-2102 Secretin, Human

05-23-2102
  
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      Overview

      Replacement Information
      Description
      OverviewSynthetic, human secretin. A strongly basic gastrointestinal peptide hormone that stimulates the secretion of bicarbonate-rich pancreatic fluid. Causes a dose-dependent increase in cAMP accumulation in pancreatic duct lines.
      Catalogue Number05-23-2102
      Brand Family Calbiochem®
      References
      ReferencesMarino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
      Villanger, O., et al. 1995. Gastroenterology 108, 850.
      Product Information
      CAS number1393-25-5
      FormWhite to off-whit lyophilized solid
      FormulationSold on the basis of peptide content.
      Hill FormulaC₁₃₀H₂₂₀N₄₄O₄₀
      Chemical formulaC₁₃₀H₂₂₀N₄₄O₄₀
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSVS4010000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MSDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      05-23-2102

      References

      Reference overview
      Marino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
      Villanger, O., et al. 1995. Gastroenterology 108, 850.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      Description

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.






      Synthetic, human secretin. A strongly basic gastrointestinal peptide hormone that stimulates the secretion of bicarbonate-rich pancreatic fluid. Causes a dose-dependent increase in cAMP-accumulation in pancreatic duct cell lines (mean effective concentration = 15 nm). Increases plasma membrane chloride permeability.
      FormWhite to off-whit lyophilized solid
      FormulationSold on the basis of peptide content.
      CAS number1393-25-5
      RTECSVS4010000
      Chemical formulaC₁₃₀H₂₂₀N₄₄O₄₀
      Peptide SequenceH-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH₂
      Purity≥95% by HPLC
      Solubility5% Acetic Acid (1 mg/ml) or H₂O (1 mg/ml)
      Storage -20°C
      Protect from moisture
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 8421
      ReferencesMarino, L.R., and Cotton, C.U. 1996. Am. J. Physiol. 270, G676.
      Villanger, O., et al. 1995. Gastroenterology 108, 850.