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Chromolith HPLC

Detailed information about Chromolith® HPLC columns

Benefits of Chromolith® HPLC columns at a glance

1. Speed of analysis

  • Separations two times faster at half the column back-pressure compared to 5 μm columns
  • Higher sample throughput – separations up to nine times faster if required
  • Fast column re-equilibration between analyses

2. Flow flexibility and flow gradients

  • Quick response to the flow change
  • Wide optimal flow ranges

3. Improved HPLC system security: robustness, reliability and versatility

  • Significantly increased column lifetime
  • Reduced maintenance on HPLC pump and injector seals
  • Reduced need for sample preparation as columns are very resistant to blocking (even with biological samples)

4. Column length no longer pressure limited

5. Cost savings from increased sample throughput can justify the expense of a method revalidation within one month.

6. Standard HPLC instruments are ideally suited for use with Chromolith® HPLC columns

  • Chromolith® columns cladded in PEEK are very easy to use and handle


Further suggested reading 

Chromolith® HPLC  
  Detailed information about Chromolith®
HPLC columns
    Cost saving
    Flow programming
    High separation efficiency
    Optimal flow range
    Robustness, reliability and versatility
    Speed of analysis
  Chromolith® CapRod®  
  Chromolith® column coupler  
  Chromolith® HPLC FastGradient  
  Chromolith® HPLC guard cartridges  
  Chromolith® NH2  
  Chromolith® Prep  
  Chromolith® RP-8 endcapped  
  Chromolith® RP-18 endcapped  
  Chromolith® RP-18 endcapped HighResolution  
  Chromolith® Si  
  Chromolith® SemiPrep  

© Merck KGaA, Darmstadt, Germany, 2014


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