Amino thiols attached to 4-methoxytrityl resin


These acid-labile resins are ideal for the preparation of N-acyl or N-alkyl aminoalkylthiols. The free amino functionality of the resin bound aminothiol can be readily acylated using standard methods of amide bond formation, or reductively alkylated. Cleavage can be effected with 1% TFA in DCM containing 5% triethylsilane. Disulfides can also be generated using electrophilic oxidants such as I2 or Tl3+.

Products in this category:
Catalog number Products
856095 4-Aminobutanethiol 4-methoxytrityl resin  Novabiochem®
856087 Cysteamine 4-methoxytrityl resin  Novabiochem®

© Merck KGaA, Darmstadt, Germany, 2014


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