Parteck® M – directly compressible mannitol
Advanced technology for excellent tabletting properties
Mannitol is a sugar alcohol that is especially suitable as an excipient for advanced, highly active APIs thanks to its non-hygroscopicity and low content of reducing sugars. Merck's outstanding, directly compressible mannitol Parteck® M is your best choice – especially if your tabletting aims at rapid release of high-dose or low-dose actives. Parteck® M has been developed under Merck’s advanced Functional Particle Engineering™ concept and is available in two different particle size distributions: Parteck® M 100 and Parteck® M 200.
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Parteck® – excipients with unique properties
Parteck® M belongs to our Parteck® product family of excipients with unique particle properties developed within our Functional Particle Engineering® concept. This concept comprises a number of proprietary technologies which allow us to offer specialty excipients with outstanding functionalities especially for the design of solid dosage forms.
Parteck® M: Directly compressible mannitol
The extraordinary properties of Parteck® M mannitol allow you to press hard, high-quality tablets directly without the need for additives. This way you achieve compact, more concentrated tablets with fewer process steps and only low compression forces – thereby minimizing wear on your tabletting equipment. Its good compressibility and rapid dissolution of actives makes Parteck® M the perfect tabletting diluent – in particular for tabletting high doses of poorly compressible actives without compromising tablet quality. Of course, Parteck® M can also be used for low-dose formulation where dose uniformity and mix homogeneity are of utmost importance. Moreover, the excellent flowability of Parteck® M enables a stable and high-throughput process.
Rapid disintegration
The unique particle structure of Parteck® M and greatly increased surface area compared to standard mannitol facilitate fast disintegration of even the hardest tablets – much faster than tablets containing any other commercially available DC-mannitol. In addition, the release of APIs is accelerated.
EMPROVE®: Qualification and registration support
Like most Parteck® excipients, our directly compressible mannitol Parteck® M bears the EMPROVE® exp trademark. EMPROVE® stands for highest product quality combined with comprehensive regulatory support: Our comprehensive EMPROVE® dossiers offer detailed, usage-specific documentation that support your qualification and registration processes.
For more information, please contact us.
