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Purospher® - High-purity HPLC columns

Purospher® STAR RP-18 endcapped

Purospher® STAR RP-18 endcapped

The versatility you need!

Purospher® STAR RP-18 endcapped HPLC columns are designed for universal use. Basic, neutral, metal chelating could easily be separated with simple mobile phases – naturally without peak tailing!

Thanks to its outstanding performance and stability, Purospher® STAR RP-18 endcapped offers maximum flexibility in method development. Robust methods can be developed over the entire pH range from 1.5 to 10.5. The high pH-stability up to pH 10.5 allows the separation of strongly basic compounds with alkaline eluents.

The combination of high purity silica, best all-round retention characteristics, outstanding pH stability up to pH 10.5, and suitability for up to 100% aqueous mobile phases, make Purospher® STAR RP-18 endcapped an all-round top performance column, almost universal in its range of applications.

Experience the performance of Purospher® STAR RP-18 endcapped
Key performance benefits:
  • Fast method development of complex samples across the pH range from 1.5 to 10.5 at different mobile phases and temperature conditions.
Specification of Purospher® STAR RP-18 endcapped
Sorbent characteristics High purity silica with polymeric C18 modification and endcapping
Metal content Na, Ca, Mg, Al: 1 ppm; Fe: 3 ppm
Particle shape spherical
Particle size 2 µm, 3 μm and 5 μm
Pore size 120 Å (12 nm)
Pore volume 1.1 mL/g
Spec. surface area 330 m²/g
Carbon load 17 % C
Coverage of the surface 3 μmol/m²
pH range pH 1.5 - 10.5
Efficiency 5 μm: > 90.000 N/m; 3 μm: > 130.000 N/m, 2 µm > 180.000 N/m
Shipping eluent Acetonitrile/Water
Surface chemistry of Puropsher® STAR RP-18 endcapped
The polymeric surface modification of Purospher® STAR RP-18 endcapped provides a nearly perfect coverage of the surface.
This prevents from silanophilic interactions.
Surface chemistry of Puropsher® STAR RP-18 endcapped
Key applications are:
Purospher® STAR 4 Pharma
Purospher® STAR 4 Food & Beverage

© Merck KGaA, Darmstadt, Germany, 2012


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