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Chromolith HPLC

Chromolith® Si HPLC column

Chromolith® Si HPLC columns

Based on high-purity silica, Chromolith® Si HPLC column has been developed as a monolithic normal-phase material suitable for separating polar non-ionic organic compounds, but with all of the benefits of the monolithic silica technology:

  • High throughput at high flow rates with the best overall column quality
  • The possibility to use flow gradients
  • Added column performance by column coupling
  • A rigid monolithic structure for a longer lifetime
  • Lower matrix sensitivity


Click here to review example applications with Chromolith® Si HPLC columns.


Specifications of Chromolith® Si HPLC columns

Silica type High-purity
Particle size Monolithic
Macropore size 2 μm
Mesopore size 13 nm (130 Å)
Pore volume 1 mL/g
Total porosity > 80%
Surface area 300 m2/g


Ordering Information – Chromolith® Si HPLC column

  100x4.6 mm
Chromolith® Performance Si 1.51465.0001


Further suggested reading 

Chromolith® HPLC  
  Detailed information about Chromolith®
HPLC columns
  Chromolith® CapRod®  
  Chromolith® column coupler  
  Chromolith® HPLC FastGradient  
  Chromolith® HPLC guard cartridges  
  Chromolith® NH2  
  Chromolith® Prep  
  Chromolith® RP-8 endcapped  
  Chromolith® RP-18 endcapped  
  Chromolith® RP-18 endcapped HighResolution  
  Chromolith® Si  
  Example applications using
Chromolith® Si HPLC columns
  Chromolith® SemiPrep  

© Merck KGaA, Darmstadt, Germany, 2014


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