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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
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19 June 2013
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A platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Reported to sensitize glioma cells to TNF-α-induced apoptosis.
| Product information | |||
|---|---|---|---|
| Form | Yellow solid | ||
| Molar mass | 300.0 | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | Pt(NH3)2Cl2 | ||
| RTECS | TP2450000 | ||
| CAS number | 15663-27-1 | ||
| Merck USA index | 14, 2317 | ||
| Store and ship information | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Toxic & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-24-37-45-53 Do not breathe dust. Avoid contact with skin. Wear suitable gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Avoid exposure - obtain special instructions before use. |
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| R Phrase |
R: 25-36/37/38-45-42/43 Toxic if swallowed. Irritating to eyes, respiratory system and skin. May cause cancer. May cause sensitization by inhalation and skin contact. |
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