189422
Australine, Hydrochloride, Castanospermum australe
(1R,2R,3R,7S,7aR)-3-Hydroxymethyl-1,2,7-trihydroxypyrrolizidine
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Faks: +49 6151 72 2000
31 May 2012
memuat
This product has been discontinued.
Please refer to our complete listing of protease glycoprotein processing and trafficking inhibitors for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A polyhydroxylated pyrrolizidine alkaloid that inhibits α-glucosidase, amyloglucosidase, and glucosidase I. Appears to be the first glucosidase inhibitor that is active toward glucosidase I but not glucosidase II. Inhibits glycoprotein processing at the glucosidase I step, resulting in the accumulation of glycoproteins containing Glc3Man7-9(GlcNAc)2-oligosaccharides. Does not inhibit α- or β-galactosidase, β-glucosidase, or α- or β-mannosidase.
| Informasi produk | |||
|---|---|---|---|
| Form | Crystalline solid | ||
| Primary Target | glucosidase 1 | ||
| Hygrocopic | Ya | ||
| Purity | ≥95% by TLC | ||
| Formulasi kimia | C8H15NO4 · HCl | ||
| Nomor CAS | 186766-07-4 | ||
| Simpan dan kirim informasi | |||
|---|---|---|---|
| Penyimpanan | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Irritant |
||
| Informasi keselamatan kerja | |||
|---|---|---|---|
| Frase S |
S: 26-36 |
||
| Frase R |
R: 36/37/38 |
||
