203729
(+)-Brefeldin A, Eupenicillium brefeldianum
1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one
ご質問については、カスタマーサービスまでご連絡ください。
メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function. Inhibitor of HDL-mediated cholesterol efflux. Causes disassembly of the Golgi complex and ER swelling in a variety of mammalian cell lines at <40 ng/ml. Blocks binding of ADP-ribosylation factor to the Golgi and inhibits the GDP-GTP exchange. Inhibits the activity of BIG1 and BIG2, the guanine-nucleotide exchange proteins for ADP-ribosylation factors.
| 製品情報 | |||
|---|---|---|---|
| Form | White crystalline solid | ||
| Purity | ≥95% by HPLC | ||
| 化学式 | C16H24O4 | ||
| RTECS | GY8410000 | ||
| CAS 番号 | 20350-15-6 | ||
| Merck USA index | 14, 1369 | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| 安全性情報 | |||
|---|---|---|---|
| S フレーズ |
S: 36 |
||
| R フレーズ |
R: 20/21/22 |
||
