189422
Australine, Hydrochloride, Castanospermum australe
(1R,2R,3R,7S,7aR)-3-Hydroxymethyl-1,2,7-trihydroxypyrrolizidine
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メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
This product has been discontinued.
Please refer to our complete listing of protease glycoprotein processing and trafficking inhibitors for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A polyhydroxylated pyrrolizidine alkaloid that inhibits α-glucosidase, amyloglucosidase, and glucosidase I. Appears to be the first glucosidase inhibitor that is active toward glucosidase I but not glucosidase II. Inhibits glycoprotein processing at the glucosidase I step, resulting in the accumulation of glycoproteins containing Glc3Man7-9(GlcNAc)2-oligosaccharides. Does not inhibit α- or β-galactosidase, β-glucosidase, or α- or β-mannosidase.
| 製品情報 | |||
|---|---|---|---|
| Form | Crystalline solid | ||
| Primary Target | glucosidase 1 | ||
| Hygrocopic | はい | ||
| Purity | ≥95% by TLC | ||
| 化学式 | C8H15NO4 · HCl | ||
| CAS 番号 | 186766-07-4 | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Irritant |
||
| 安全性情報 | |||
|---|---|---|---|
| S フレーズ |
S: 26-36 |
||
| R フレーズ |
R: 36/37/38 |
||
