239777
Cyclophilin A, Human, Recombinant, E. coli
Peptidylproline cis-trans-Isomerase
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メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
Recombiant, human cyclophilin A expressed in E. coli. An ubiquitous enzyme that catalyzes the cis-trans-isomerization of X-Pro peptide bonds. Binds to proteins and acts as a chaperone in protein folding. Incorporates into HIV-1 virons and is believed to be essential for viral infectivity. Cyclophilin binds to the immunosuppressant Cyclosporin A (Cat. No. 239835). This complex then binds calcineurin (PP2B) and inhibits its phosphatase activity.
| 製品情報 | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 20 mM Tris-HCl, pH 7.8. | ||
| Purity | ≥90% by SDS-PAGE | ||
| EC 番号 | 5.2.1.8 | ||
| CAS 番号 | 95076-93-0 | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Blue Ice Only
Standard Handling |
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| 安全性情報 | |||
|---|---|---|---|
| S フレーズ |
S: 24/25-36 |
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