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メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
Cyclic oligopeptide with immunosuppressant properties. Induces apoptosis in rat thymocytes and in the murine B cell lymphoma cell line, WEH1-231. However, prevents anti-IgM and ionomycin-induced apoptosis in BLB cell lines. The complex of cyclosporin A with cyclophilin inhibits protein phosphatase 2B with nanomolar affinity. Inhibits nitric oxide synthesis induced by interleukin-1α, lipopolysaccharides, and TNF-α. Induces cardiomyocytes from embryonic stem cells.
| 製品情報 | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Primary Target | NOS induced by interlukin-1-α | ||
| Purity | ≥97% (dry basis) | ||
| 化学式 | C62H111N11O12 | ||
| RTECS | GZ4120000 | ||
| CAS 番号 | 59865-13-3 | ||
| Merck USA index | 14, 2752 | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Carcinogenic / Teratogenic |
||
| 安全性情報 | |||
|---|---|---|---|
| S フレーズ |
S: 22-24/25-36/37 |
||
| R フレーズ |
R: 40 |
||
