344510
FTase Inhibitor I
N-[2(S)-[2(R)-Amino-3-mercaptopropylamino]-3-methylbutyl]-Phe-Met-OH, B581
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メルク株式会社
目黒区下目黒1-8-1
153-8927 東京
Japan
TEL： 0120-189-390
Fax: 0120-189-350
E-mail mj_service@merckgroup.com
31 5月 2012
ローディング
A potent, cell-permeable, selective, peptidomimetic inhibitor of farnesyltransferase (FTase) that is approximately 37-fold more active against FTase (IC50 = 21 nM in vitro) than against geranylgeranyltransferase (GGTase; IC50 = 790 nM). Very resistant to proteolysis.
| 製品情報 | |||
|---|---|---|---|
| Form | White solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | FTase | ||
| Primary Target IC50 | 21 nM in vitro | ||
| Secondary target | GGTase (IC50 = 790 nM) | ||
| Hygrocopic | はい | ||
| Packaged under inert gas | はい | ||
| Cell permeable | はい | ||
| Purity | ≥90% by HPLC | ||
| 化学式 | C22H38N4O3S2 | ||
| 保管と送付情報 | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
