For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
We are offering 14-3-3γ, GST-Fusion, Human, Recombinant, E. coli (Cat. No. 100072) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.
Recombinant, human 14-3-3β, fused to GST at the N-terminus with a thrombin cleavage site and expressed in E. coli. Useful for protein-protein interaction assays and gel overlays. The 14-3-3 protein family consists of a group of highly conserved proteins that may regulate the function of signal transduction complexes by modulating their enzymatic activity, conformation, stability, and/or intracellular localization. 14-3-3β plays an important role in the proliferation and oncogenic transformation of NIH3T3 cells through enhancement of Raf-1 activation and resultant augmentation of signaling in the MAPK cascade.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 150 mM NaCl, 50 mM Tris-HCl, pH 7.5. | ||
| Molar mass | 60000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥90% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
