For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
Please refer to our listing of other apoptosis inducers for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A naphthoquinone analog that induces apoptosis in HeLa cells via the negative regulation of cell survival through caspase-3-mediated cleavage of p65/RelA subunit of NF-κB at Asp97. Also causes a potent growth arrest in human hepatocarcinoma cells without generating any ROS.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Molar mass | 259.1 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C10H4Cl2O4 | ||
| CAS number | 14918-69-5 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
||
| R Phrase |
R: 20/21/22-36/37/38 Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. |
||
