For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
Please refer to our complete listing of telomerase inhibitors for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A reverse transcriptase (RT) inhibitor with antiviral properties. Has been shown to cause a consistent and rapid telomere shortening in vegetatively growing Tetrahymena. Reduces the proliferation of Jurkat and L1210 cell lines as well as human peripheral blood mononuclear cells at ~250 µM level. In combination with 5-fluorouracil, d4T yields supra-additive cytotoxic effects in colon cancer (WiDr) and breast cancer (MCF-7) cell lines.
| Product information | |||
|---|---|---|---|
| Form | White solid | ||
| Primary Target | reverse transcriptase | ||
| Secondary target | blood mononuclear cell activity (IC50 = 250 µM) | ||
| Molar mass | 224.2 | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥99% by HPLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C10H12N2O4 | ||
| CAS number | 3056-17-5 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
