189825
5-Aza-2′-Deoxycytidine
5-Aza-CdR, 5-Aza-dC, 2'-Deoxy-5-azacytidine, Decitabine
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors.
| Alternatives | |
|---|---|
| 691400 | Zebularine |
| Alternative products for 5-Aza-2′-Deoxycytidine | |
| 691400 | Zebularine |
| Accessories for 5-Aza-2′-Deoxycytidine |
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Primary Target | DNA methyltransferase inhibitor | ||
| Molar mass | 228.2 | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥ 98% by HPLC | ||
| Solubility | MeOH, DMSO, or 50% Acetic Acid | ||
| Chemical formula | C8H12N4O4 | ||
| RTECS | XZ3012000 | ||
| CAS number | 2353-33-5 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 22-26-36/37/39-45 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 20/21/22-36/37/38-43-61 Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. May cause harm to the unborn child. |
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