171581
Aβ40 Fibrillogenesis Inhibitor
Amyloid β40 Fibrillogenesis Inhibitor, Aβ16-20m, Ac-K(Me)LV(Me)FF-NH2
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
We apologize for the inconvenience, but we do not currently have an alternative product.
For related products, please refer to our complete listing of amyloidogenesis inhibitors.
A membrane-permeable pentapeptide based on the core domain of β-Amyloid (Aβ) that contains N-methyl amino acids in alternate positions. Acts as a selective inhibitor of Aβ40 fibrillogenesis and disassembles preformed fibrils (IC50 expressed as a molar ratio of inhibitor to Aβ40 = 6.9 and 7.8, respectively). Exists as a monomer in solution and appears to function as a β-sheet breaker. Displays greater stability towards denaturation and is resistant to chymotrypsin.
| Product information | |||
|---|---|---|---|
| Form | White lyophilized solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | AB40 | ||
| Molar mass | 721.9 | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Cell permeable | Yes | ||
| Purity | ≥95% by HPLC | ||
| Solubility | H2O | ||
| Chemical formula | C39H59N7O6 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
||
