171589
Aβ42 Fibrillogenesis Inhibitor IV
Amyloid β42 Fibrillogenesis Inhibitor IV, Ac-LP-(NMe)-FFD-NH2, iAβ5p-A1
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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A modified (N-methylated amide linkage between Pro and Phe) analog of the end protected Aβ42 Fibrillogenesis Inhibitor III (Cat. No. 171588) that acts as a β-sheet breaker with improved brain uptake and increased in vivo metabolic stability (t1/2 > 24 hours in human plasma and in rat brain homogenate).
| Product information | |||
|---|---|---|---|
| Peptide Sequence | Ac-Leu-Pro(N-CH3)Phe-Phe-Asp-NH2 | ||
| Form | White lyophilized solid | ||
| Molar mass | 692.8 | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥97% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C36H48N6O8 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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