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31 May 2012
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Native aminopeptidase N purified from rat renal brush-border membranes and cleaved with papain to produce soluble enzyme. A single-chain, integral membrane protease that, functions with broad specificity to remove N-terminal amino acids from peptides. It has been reported that levels of aminopeptidase N are elevated in cancer subjects and correlate with tumor load, and thus, the enzyme is believed to play a role in angiogenesis.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 200 mM NaCl, 50 mM Tris-HCl, pH 8.0. | ||
| Molar mass | 150000 | ||
| Avoid freeze/thaw | Yes | ||
| Specific activity | ≥100 units/mg protein | ||
| Unit definition | One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol L-Leu-pNA per min at 37°C, pH 7.2 | ||
| Purity | ≥90% by SDS-PAGE | ||
| EC number | 3.4.11.2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
