176901  Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem

Anthrax LF Protease Inhibitor, Bacillus anthracis LF Protease Inhibitor, In-2-LF

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18 April 2014

Product number Qty/Pk Quantity Price
176901-1MG  1 mg  loading
Prices are subject to change without notice.
A cell-permeable N-acetylated, C-hydroxamate derivative of a 14-mer peptide designed from the MEK-2 template that acts as a competitive inhibitor of Anthrax lethal factor (LF) metalloprotease (Ki = 1 nM). Also inhibits MEK-3 cleavage. Protects against Anthrax toxin induced cytotoxicity in RAW264.7 and J772.A1 cells.
Product information
Peptide Sequence Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-NHOH
Form White lyophilized solid
Formulation Supplied as a trifluoroacetate salt.
Primary Target anthrax LF metalloprotease
Primary Target IC50 1 nM
Molar mass 1984.4
Hygrocopic Yes
Packaged under inert gas Yes
Cell permeable Yes
Purity ≥97% by HPLC
Solubility DMSO, 5% Acetic acid, or H2O
Chemical formula C81H150N42O17
Store and ship information
Storage -20°C
Ship Blue Ice Only
Standard Handling

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