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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
Please refer to our complete listing of apoptosis inducers for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A cell-permeable pyridyl compound that selectively promotes apoptosome formation and the subsequent caspase activation by antagonizing prothymosin-α (ProT), a negative regulator of mitochondria-initiated caspase activation. Shown to elevate caspase-3 activity in cancer cell extracts in a dose-dependent manner (maximum stimulation at ~ 100 to 200 µM in HeLa cell lysate).
| Product information | |||
|---|---|---|---|
| Form | Beige solid | ||
| Molar mass | 240.5 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO, MeOH, or Dilute HCl | ||
| Chemical formula | C8H8Cl3NO | ||
| CAS number | 10129-56-3 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Carcinogenic / Teratogenic |
||
