371959
Apoptosis Activator V, Isoapoptolidin
Isoapoptolidin, Nocardiopsis sp.
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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A cell-permeable ring-expanded macrolide isomer of Apoptolidin (Cat. No. 178495) with over 20-fold less inhibitory activity against F0F1-ATPase (IC50 = 17 µM in yeast). Isoapoptolidin quickly isomerizes to and co-exists with Apoptolidin in equilibrium (k1 = 0.0626 h-1 and Keq = 0.638 in Dulbecco's PBS at 37°C).
| Product information | |||
|---|---|---|---|
| Form | White lyophilized solid | ||
| Molar mass | 1129.4 | ||
| Protect from Light | Yes | ||
| Protect from Moisture | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥90% by HPLC | ||
| Solubility | DMSO, EtOH, or MeOH | ||
| Chemical formula | C58H96O21 | ||
| CAS number | 476647-30-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Shipped with Blue Ice or with Dry Ice
Harmful |
||
