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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Synthetic [Arg8]-Vasopressin. An antidiuretic peptide hormone. Released from the hypothalamus during stress. Although noted primarily for its hemodynamic and hemostatic properties, it appears to affect the immune system. Acts via the activation of the adenylate cyclase system resulting in increased cAMP levels (EC50 = 34 nM). Reported to induce an increase in [Ca2+]i in hippocampal neurons via action of VI vasopressin receptors coupled with N-type Ca2+ channels.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | H-Cys¹-Tyr-Phe-Gln-Asn-Cys6-Pro-Arg-Gly-NH2 (disulfide bond: 1 → 6) | ||
| Form | Lyophilized | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 1084.2 | ||
| Protect from Moisture | Yes | ||
| Purity | ≥97% by HPLC | ||
| Sold on the basis of peptide content | Yes | ||
| Solubility | H2O | ||
| Chemical formula | C46H65N15O12S2 | ||
| CAS number | 113-79-1 | ||
| Merck USA index | 14 9938 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
||
| R Phrase |
R: 20 Harmful by inhalation. |
||
