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31 May 2012
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A gold(I) compound that inhibits the activity of IKK (ID50 = 10.9 µM) and disrupts PB1 (Phox and Bem1p) domain-mediated interactions between Par6 and PKCι (IC50 = ~ 1 µM) by modifying cysteine residues within the catalytic domain of IKK and the PB1 domain of PKCι. Inhibits PKCι-dependent Rac1 activation in A549 cells.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Molar mass | 368.1 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% (Gold content) | ||
| Solubility | H2O | ||
| Chemical formula | C4H4AuNaO4S | ||
| CAS number | 12244-57-4 | ||
| Merck USA index | 14, 4518 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
