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Merck KGaA
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64293 Darmstadt
Germany
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24 mayo 2013
cargando
Non-phosphorylatable analog of Autocamtide-2 (Cat. No. 189475) that acts as a highly specific and potent inhibitor of calmodulin-dependent protein kinase II (IC50 = 40 nM). It is about 50 times more potent than [Ala286]-CaM kinase II Inhibitor, 281-301 (Cat. No. 208710). Has no effect on PKA, PKC, and CaM kinase IV. Blocks Ca2+-induced insulin secretion from electropermeabilized islets.
| Información sobre producto | |||
|---|---|---|---|
| Peptide Sequence | H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH | ||
| Form | White solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | cam Kinase-2 | ||
| Primary Target IC50 | 40 nM | ||
| Masa molar | 1497.8 | ||
| Hygrocopic | Si | ||
| Purity | ≥97% by HPLC | ||
| Solubilidad en agua | H2O | ||
| Fórmula químico | C64H116N22O19 | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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