203671
Bongkrekic Acid, Triammonium Salt
3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic Acid, BA, 3NH4
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Acts as a ligand of the adenine nucleotide translocator. A potent inhibitor of mitochondrial megachannel (permeability transition pore). Significantly reduces signs of apoptosis induced by nitric oxide. Prevents the apoptotic breakdown of the inner mitochondrial transmembrane potential (ΔΨm), as well as a number of other phenomena linked to apoptosis.
| Product information | |||
|---|---|---|---|
| Form | Beige-pink solid | ||
| Primary Target | mitochondrial mega channel | ||
| Molar mass | 537.7 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥92% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C28H35O7 · 3NH4 | ||
| CAS number | 1177154-51-6 | ||
| Merck USA index | 14, 1332 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Dry Ice Only
Harmful & Carcinogenic / Teratogenic |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36-22 Wear suitable protective clothing. Do not breathe dust. |
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| R Phrase |
R: 20/21/22-40 Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. |
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