851004
BOP
Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate Novabiochem®
01-62-0001;Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphoniumhexafluorophosphate,Castro's Reagent
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Peptide coupling reagent which suppresses enantiomerization [1-15]. Reduction of carboxylic acids activated with BOP provides a facile route to alcohols [16].
Novabiochem® recommends the replacement of BOP by PyBOP®(for PyBOP® please see 01-62-0016). The manufacture of BOP, as well as its utilization, involves the use or the formation of hexamethylphosphotriamide, the carcinogenicity and respiratory toxicity of which has been the subject of numerous reports.
The product number for this product was previously 01-62-0001.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please click here; otherwise please use the option in the "About this product" menu.
Novabiochem® recommends the replacement of BOP by PyBOP®(for PyBOP® please see 01-62-0016). The manufacture of BOP, as well as its utilization, involves the use or the formation of hexamethylphosphotriamide, the carcinogenicity and respiratory toxicity of which has been the subject of numerous reports.
The product number for this product was previously 01-62-0001.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please click here; otherwise please use the option in the "About this product" menu.
| Product information | |||
|---|---|---|---|
| Molar mass | 442.28 g/mol | ||
| EC number | 260-279-1 | ||
| CAS number | 56602-33-6 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2 to +8°C | ||
| Safety information according to GHS | |||
|---|---|---|---|
| Hazard Statement(s) |
H335: May cause respiratory irritation. H315: Causes skin irritation. H319: Causes serious eye irritation. |
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| Precautionary Statement(s) |
P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
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| Hazard Pictogram(s) |
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| Storage class | 10 - 13 Other liquids and solids | ||
| WGK | WGK 3 highly water endangering | ||
| Safety information | |||
|---|---|---|---|
| R Phrase |
R 36/37/38 Irritating to eyes, respiratory system and skin. |
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