208734
Calmodulin Binding Domain
Calmodulin antagonist, CaM kinase II 290-309
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Potent calmodulin antagonist. Inhibits activation of calmodulin-dependent protein kinase II (IC50 = 52 nM). Interacts with the catalytic core of CaM kinase II as a pseudosubstrate.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH | ||
| Form | White lyophilized solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | calmodulin dependent PK-2 | ||
| Primary Target IC50 | 52 nM | ||
| Secondary target | calmodulin dependent phosphodiesterase (IC50 = 1.1 nM) | ||
| Molar mass | 2274.3 | ||
| Hygrocopic | Yes | ||
| Purity | ≥95% by HPLC | ||
| Sold on the basis of peptide content | Yes | ||
| Solubility | H2O | ||
| Chemical formula | C103H185N31O24S | ||
| CAS number | 115044-69-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
