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Merck KGaA
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64293 Darmstadt
Germany
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19 junio 2013
cargando
A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity). Exhibits inhibitory activity across converged species, including rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM). Does not affect the activities of CaMK I, CaMK IV, CaMKK, PKA, or PKC. The peptide sequence corresponds to the inhibitory domain of CaMK IIN.
| Información sobre producto | |||
|---|---|---|---|
| Peptide Sequence | H-Lys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys-OH | ||
| Form | Off-white solid | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Primary Target | cam Kinase-2 | ||
| Primary Target IC50 | 50 nM | ||
| Secondary target | rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM) | ||
| Masa molar | 3115.7 | ||
| Hygrocopic | Si | ||
| Packaged under inert gas | Si | ||
| Purity | ≥95% by HPLC | ||
| Solubilidad en agua | DMSO | ||
| Fórmula químico | C136H240N44O39 | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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