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31 May 2012
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Protonophore. Uncoupling agent for oxidative phosphorylation that inhibits mitochondrial function. Approximately 100 times more effective than 2,4-dinitrophenol. Binds with cytochrome c oxidase with high affinity (Kd = 270 nM). Inhibits transport processes and depresses growth.
| Product information | |||
|---|---|---|---|
| Form | Yellow solid | ||
| Primary Target | cytochrome c oxydase | ||
| Primary Target Ki | kd = 270 nM | ||
| Molar mass | 204.6 | ||
| Purity | ≥95% by HPLC | ||
| Solubility | DMSO or EtOH | ||
| RTECS | FG5600000 | ||
| CAS number | 555-60-2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
||
| R Phrase |
R: 20/21/22-36/37/38 Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. |
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