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31 May 2012
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An antifungal antibiotic that inhibits sterol and fatty acid biosynthesis. In fatty acid synthesis, reported to bind in equimolar ratio to β-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. Also shown to inhibit feeding and induce dramatic weight loss in mice.
| Product information | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Primary Target | sterol & fatty acid biosynthesis | ||
| Molar mass | 223.3 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by TLC | ||
| Solubility | EtOH or DMSO | ||
| Chemical formula | C12H17NO3 | ||
| RTECS | JR1670000 | ||
| CAS number | 17397-89-6 | ||
| Merck USA index | 14, 2004 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
||
| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
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