For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
We are offering Cholera Toxin, Vibrio cholerae, Type Inaba 569B, Azide Free (Cat. No. 227036) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.
Useful for studies involving adenylate cyclase, AMP, and related membrane-transport phenomena. Consists of a single A subunit surrounded by five polypeptide chains of the B subunits. The A subunit catalyzes the ADP-ribosylation of the α-subunit of G-proteins, reducing intrinsic GTPase activity and activating the α-subunit. The B subunits are responsible for the attachment of the native toxin on the cell surface.
| Product information | |||
|---|---|---|---|
| Form | Solid | ||
| Formulation | Lyophilized from 200 mM NaCl, 50 mM Tris, 3 mM NaN3, 1 mM EDTA, pH 7.5. | ||
| Molar mass | 84000 | ||
| Do not freeze | Yes | ||
| Specific activity | ≥ a standard cholera toxin preparation as determined using a hemagglutination assay | ||
| Purity | Single band by disc gel electrophoresis | ||
| Solubility | Sterile dH2O | ||
| RTECS | LF3100000 | ||
| CAS number | 9012-63-9 | ||
| Declaration | Not available for sale outside of the United States. | ||
| Store and ship information | |||
|---|---|---|---|
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Highly Toxic |
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| End use certificate | To purchase this product, the completion of a "Select Agent Declaration" and/or "End-Use Certificate" is required. Once your sales order is placed, our Regulatory Specialist will be contacting the end-user of this product to complete the required form(s). Please ensure to provide the customer service representative with the end-user's name, telephone number, fax number and e-mail address to prevent delivery delays. (Note: the completed form must be returned within five (5) business days from receipt and will be valid for one year from the date of signing.) | ||
| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 7-36/37 Keep container tightly closed. Wear suitable protective clothing and gloves. |
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| R Phrase |
R: 21/22-36/37/38 Harmful in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. |
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