For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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This product has been discontinued.
We apologize for the inconvenience, but we do not currently have an alternative product.
For related products please refer to our complete listing of general proteases.
Native chymase, a chymotrypsin-like serine protease, purified from human skin mast cells. Released from granules during mast cell activation. Facilitates angiogenesis in sponge granulation tissues via local production of angiotensin II, which upregulates VEGF. Known to cleave fibronectin, vitronectin, and procollagen in vivo. Tight binding to heparin proteoglycan causes the enzyme to act at a higher activity towards natural and peptide substrates.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 1 M NaCl, 50 mM sodium acetate buffer, pH 5.0. | ||
| Molar mass | 30000 | ||
| Avoid freeze/thaw | Yes | ||
| Specific activity | ≥30 units/mg protein | ||
| Unit definition | One unit is defined as the amount of enzyme that will hydrolyze 0.1 µmol of N-benzoyl-L-tyrosine-ethyl ester (BTEE) per min at 25°C pH 7.8. | ||
| Purity | ≥95% by SDS-PAGE | ||
| Source | Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
