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31 May 2012
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An antifungal agent that acts as a potent and specific inhibitor of the Ca2+-activated K+ channel (Gardos channel; IC50 = 650 nM). Prevents K+ loss and dehydration of sickled erythrocytes.
| Product information | |||
|---|---|---|---|
| Form | Off-white solid | ||
| Molar mass | 344.8 | ||
| Purity | ≥98% by TLC | ||
| Solubility | DMSO or MeOH | ||
| Chemical formula | C22H17ClN2 | ||
| RTECS | NI4377000 | ||
| CAS number | 23593-75-1 | ||
| Merck USA index | 14, 2417 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
||
| R Phrase |
R: 22-36/38 Harmful if swallowed. Irritating to eyes and skin. |
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