324380
Doxorubicin, Hydrochloride
Adriamycin, 14-Hydroxydaunomycin, HCl
Wenn Sie allgemeine Fragen haben, wenden Sie sich bitte an unseren Kundenservice:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Fax: +49 6151 72 2000
31 Mai 2012
wird geladen
Antitumor antibiotic and a highly effective myotoxin that inhibits topoisomerase II (IC50 = 100 nM). Binds to nucleic acids, presumably by specific intercalation into the DNA double helix, thereby inhibiting nucleic acid synthesis. Induces apoptosis in rhabdomyosarcoma cell lines.
| Produktinformationen | |||
|---|---|---|---|
| Form | Red solid | ||
| Primary Target | topoisomerase 2 | ||
| Primary Target IC50 | 100 nM | ||
| Protect from Light | Ja | ||
| Hygrocopic | Ja | ||
| Purity | ≥95% by HPLC | ||
| Chemische Formel | C27H29NO11 · HCl | ||
| RTECS | QI9295900 | ||
| CAS-Nummer | 25316-40-9 | ||
| Merck USA index | 14, 3439 | ||
| Lager- und Versandinformationen | |||
|---|---|---|---|
| Lagerkategorie | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Carcinogenic / Teratogenic |
||
| Sicherheitshinweise | |||
|---|---|---|---|
| S-Satz |
S: 36/37-45-53-22-28 |
||
| R-Satz |
R: 45-46 |
||
