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01 June 2012
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A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPγS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
| Product information | |||
|---|---|---|---|
| Form | Solid | ||
| Molar mass | 343.9 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by TLC | ||
| Solubility | DMSO or EtOH | ||
| Chemical formula | C19H33NO2 • HCl | ||
| CAS number | 162359-56-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Shipped with Blue Ice or with Dry Ice
Standard Handling |
||
