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01 June 2012
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A pentapeptide based on the carboxyl terminus of H-Ras with a dansyl group attached to the amino terminus. Serves as a fluorescent substrate for continuously monitoring fluorescent protein-geranylgeranyltransferase (type I) (GGTase-I) activity (Km = 5 µM) in the presence of geranylgeranyl diphosphate. S-geranylgeranylation of the cysteine moiety results in a significant enhancement in fluorescence intensity (monitored at λ = 460 nm). Reported to be highly selective for GGTase and is not recognized by FTase.
| Product information | |||
|---|---|---|---|
| Form | Lyophilized | ||
| Formulation | Supplied as a trifluoroacetate salt. | ||
| Molar mass | 736.9 | ||
| Protect from Light | Yes | ||
| Hygrocopic | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥95% by HPLC | ||
| Excitation max. | ~360 nm | ||
| Emission max. | ~460 nm | ||
| Solubility | DMSO | ||
| Chemical formula | C34H52N6O8S2 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Blue Ice Only
Standard Handling |
||
