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01 June 2012
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A serine protease associated with perforin in killer T thymocytes and natural killer (NK) cells. It is involved in the perforation of target cells and initiation of proteolysis that leads the cell into the apoptosis pathway. Proteolytically activates procaspases. Granzyme B has been found in the nucleus as well as in cytoplasmic granules of killer thymocytes.
M.W. 30,000 - 32,000.
| Substitutes | |
|---|---|
| 368043 | Granzyme B, Human, Recombinant, E. coli |
| Substitutes for Granzyme B, Human, Cell Culture-Derived | |
| 368043 | Granzyme B, Human, Recombinant, E. coli |
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 150 mM NaCl. | ||
| Molar mass | 32000 | ||
| Avoid freeze/thaw | Yes | ||
| Unit definition | One unit is defined as the amount of enzyme that will hydrolyze 1.0 nmol Boc-ADD-S-Bzl (Cat. No. 368063) per min at 37°C, pH 7.0. | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
||
