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19 mayo 2013
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A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as a relevant kinase inactive control (IC50 > 92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
| Producto alternativo | |
|---|---|
| 361552 | InSolution™ GSK-3 Inhibitor IX |
| 361550 | GSK-3 Inhibitor IX |
| Productos alternativos para GSK-3 Inhibitor IX, Control, MeBIO | |
| 361552 | InSolution™ GSK-3 Inhibitor IX |
| 361550 | GSK-3 Inhibitor IX |
| Accesorios para GSK-3 Inhibitor IX, Control, MeBIO |
| Información sobre producto | |||
|---|---|---|---|
| Form | Dark red solid | ||
| Primary Target | GSK-3α/β | ||
| Primary Target IC50 | 5 nM | ||
| Secondary target | IC50 >92 µM for Cdk1/B, >100 µM for Cdk5/p25, and GSK-3α/β | ||
| Masa molar | 370.2 | ||
| Protect from Light | Si | ||
| Packaged under inert gas | Si | ||
| Cell permeable | Si | ||
| ATP Competitive | Si | ||
| Purity | ≥97% by HPLC | ||
| Solubilidad en agua | DMSO | ||
| Fórmula químico | C17H12BrN3O2 | ||
| Número CAS | 710323-61-8 | ||
| Almacenar y enviar información | |||
|---|---|---|---|
| Categoría de alamacenamiento | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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