382182
Histone Deacetylase 7, GST-Fusion, Human, Recombinant, S. frugiperda
HDAC7, Human, Recombinant
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Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Recombinant, human histone deacetylase 7 ( HDAC7) consisting of amino acids 518 to the C-terminus fused at the N-terminus to GST and expressed in S. frugiperda insect cells using a baculovirus expression system. HDAC7 is a class II histone deacetylase highly expressed in CD4+CD8+ double-positive thymocytes where it regulates apoptosis. The active deacetylase is useful in the study of HDAC7 regulation and for inhibitor screening.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 138 mM NaCl, 25 mM Tris-HCl, 0.05% TWEEN®-20 detergent, 10% glycerol, pH 8.0. | ||
| Molar mass | 78000 | ||
| Avoid freeze/thaw | Yes | ||
| Specific activity | ≥1 unit/µg protein | ||
| Unit definition | One unit is defined as the amount of enzyme required to deacetlyate 1 pmol fluorescent peptide substrate [Arg-His-Lys-Lys(Ac)], per min at 30°C. | ||
| Purity | ≥70% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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